Reporting owner · CIK 0001595855

Opaleye Management Inc.

Visual SEC Form 4 history across 5 companies, 25 transactions and 13 filings.

10%Sol-Gel Technologies Ltd.
Open-market mix
Filings13Form 4 records
Buying$4.9M22 purchases
Selling$1.9M3 sales
Net value$3MBuys minus sells
Companies55 securities
Most recentAug 31, 2026buy

Open-market buy performance

90-day forward return on this insider's open-market purchases

90d forward
Average return+17.3%Across 10 open-market buys
Median return0.0%Half the buys outperformed this
How it's computed

For every open-market buy (Form 4 code P, acquisition A) in the selected window, we take the closing price on the transaction date and 90 calendar days later, then compute the percentage change. The figures shown are the simple average and median of those per-buy returns.

  • Window follows the rest of the summary (all-history or last 3 months).
  • Only buys with a resolved price context are counted.
  • Includes both positive and negative outcomes; gains and losses net out at the per-buy level.

Monthly open-market activity

Reported purchase and sale transaction counts

Buys Sells
1050-5-102Dec 2421Jan 2541Feb 252Mar 2521Jan 261Feb 263May 266Aug 26

Net value flow

Buys minus sells

Dec 24
$211K
Jan 25
−$428.8K
Feb 25
$506.4K
Mar 25
$394.5K
Jan 26
−$958.1K
Feb 26
$5.8K
May 26
$434.7K
Aug 26
$2.8M

Transaction texture

Ownership and ticket size

Average P/S size$272.7K
Median P/S size$133.2K
Direct0
Indirect25
Aug 31, 2026buy

Latest Form 4 facts

Quick context from source filings

Latest transaction

buy at Sol-Gel Technologies Ltd. on Aug 31, 2026 valued at $14,995.

Review SEC filing
Latest buy

buy at Sol-Gel Technologies Ltd. on Aug 31, 2026 valued at $14,995.

Review SEC filing
TickerInsiderRoleTypeSharesValueCodeSignals90d returnFiledTrans date
HROWOpaleye Management Inc.
10%
sale20.0k-$106MS01/0801/06
SLGLOpaleye Management Inc.
10%
buy198$851kP01/0601/05
SLGLOpaleye Management Inc.
10%
buy2.39k$10.0MP01/0601/02
CDXSOpaleye Management Inc.
10%
buy100k$26.1MP03/10/202503/06/2025
HROWOpaleye Management Inc.
10%
sale5.00k-$14.0MS03/04/202502/28/2025
CDXSOpaleye Management Inc.
10%
buy47.3k$13.3MP03/04/202503/03/2025
CDXSOpaleye Management Inc.
10%
buy147k$44.1MP03/04/202502/28/2025
CDXSOpaleye Management Inc.
10%
buy15.0k$5.99MP02/13/202502/12/2025
CDXSOpaleye Management Inc.
10%
buy12.5k$5.14MP02/13/202502/11/2025
CDXSOpaleye Management Inc.
10%
buy22.5k$9.41MP02/13/202502/10/2025

Opaleye Management Inc. Insider Activity FAQ

SEC Form 4 context

Who is Opaleye Management Inc.?

Opaleye Management Inc. is a reporting owner in SEC Form 4 filings with reporting owner CIK 0001595855.

Which companies has Opaleye Management Inc. reported transactions for?

Sol-Gel Technologies Ltd., Grace Therapeutics, Inc., Alpha Cognition Inc., HARROW, INC., CODEXIS, INC.

When was Opaleye Management Inc.'s latest insider buy?

buy at Sol-Gel Technologies Ltd. on Aug 31, 2026 valued at $14,995.

When was Opaleye Management Inc.'s latest insider sale?

sale at HARROW, INC. on Jan 06, 2026 valued at $1,066,914.

Where can I see the original SEC filings?

Each transaction row links directly to the source SEC filing so the reported Form 4 details can be reviewed.

Are performance metrics included?

This version does not calculate win rates, forward returns, benchmark-adjusted returns, or high-conviction scores.